Evaluation of zinc and copper levels in vaginal tissues and whole blood: correlation with age

Abstract Background Zinc and copper are essential trace elements play a crucial role in the homeostasis of connective tissues. In this study, we aimed to define zinc levels vaginal tissue establish whether correlation exists between either or both whole blood samples finding correlates with age patient at least her menopausal status. Methods We collected from 32 women measured their by inductively coupled plasma optical emission spectrometry. have performed Student's t test evaluate differences mean multiple regression association zinc/copper age, status, number deliveries, levels. Results were significantly higher tissues than ( p < 0.01). samples, strong positive could be detected r = 0.82, tissue, negative was found for − 0.27, 0.04 0.56, Multiple linear model (age, delivery copper/zinc levels) showed that only remained significant predictor 0.03, 95% CI 2.28 0.06; 0.004, 1.76 0.34). Conclusions decline age. Out examined variables delivery, levels), is